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) use. We report two sufferers with no prior history of neurological sickness that seasoned their initially generalized tonic–clonic seizure soon after cigarette smoking Spice. The mechanism behind the probable proconvulsant result of synthetic cannabinoids is just not recognized, but it may be because of their effects at the cannabinoid receptor

Synthetic cannabinoids were made for cannabinoid research specializing in tetrahydrocannabinol (THC), cannabinoid receptors, as well as endocannabinoids that activate them in your body. Synthetic cannabinoids have been necessary partly on account of lawful restrictions on organic cannabinoids, which make them tricky to get hold of for exploration.D